Hi, Lilbit, so glad you are moving forward with the chemo. Yes, Jim had issues with his blood counts after the first 3 treatments. His oncologist chose to give him the cis/gem day 1, cis day 2 and then day 7 gemzar alone. I think that was how it went. Due to the sudden and very large drop in wbc and platelets so early on the decision to do the 3 treatments per cycle was established. Jim was given 2 weeks off when the first big drop came and there were never any other times when he needed to stop treatments. Jim was diagnosed 7/13/10 and had his RC/IC 8/12/10 and started chemo on 9/9/10. He moved fast and furiously with fighting what I refer to as "the b**tard cancer" just another way to say bladder cancer. Anyway, he as of right now is cancer free until proven otherwise! So, stay well and keep up the great job. BTW, Jim also had a few times when his vein was messed up. He actually asked the oncologist for a different nurse and then didn't have any other vein issues. He was on the cis/gem regime for 6 months so I think that's saying a lot! Take care, Lilbit and we are glad you are doing so well!