This combination has shown promise (in relatively preliminary studies) as a substitute when BCG is unavailable as well as in patients who have either failed BCG or who are unable to tolerate it. I think that it is a viable alternative.
Diagnosis 2-08 Small papillary TCC; CIS
BCG; BCG maintenance
Vice-President, American Bladder Cancer Society
So, my brother was diagnosed with bladder cancer a year and a half ago--T1HG. He's gone through BCG induction and a year of maintanence, and so far it is working: every cysto so far has been clear (including today's). However, due to the BCG shortage, he is going to have to switch to chemotherapy for further maintenance, namely, a combination of gemcitabine and doxorubicin given monthly for three months. Does anyone here have any experience with this regimen? I should mention that he tolerated the BCG amazingly well, and I am concerned about both the possible side effects and efficacy of the new chemo. Thanks in advance!