Knifedealer, I can't begin to thank you for all of the research you've completed on my behalf. I've completed the course of the steroid and either that helped or the cystitis cured itself. Right now, everything is good. Hopefully, I won't need anymore BCG treatments for the rest of my life and I won't be dealing with this issue ever again!
1 year 1 week ago - 1 year 1 week ago#58482by Knifedealer
Glad to read you may be getting some relief from the steroid. I don't think I've ever had a steroid that wasn't helpful in resolving whatever ailment for which it was prescribed. The long-term effects however, can be devastating as I'm sure you know. Regardless, I hope your issue resolves quickly.
After recommending combining piperine with turmeric, I wondered if the piperine wouldn't further irritate the bladder. After all, piperine is found in black pepper. Turmeric, or more specifically curcumin, an ingredient derived from turmeric, is known for its anti-inflammatory effects and works by decreasing the chemical moderators that produce inflammation in the body. As I noted below, the piperine in black pepper boosts the absorption of curcumin. While many sources list "spicy foods" as a bladder irritant, I searched the internet but was unable to identify evidence of a link between piperine and bladder irritation. Interesting, I found a current (US) National Cancer Institute pilot phase 1 trial that "studies the side effects and best dose of curcumin when given together with piperine ... in reducing inflammation for ureteral stent-induced symptoms in patients with cancer."
To summarize, I don't know for certain if the piperine I recommended to be added to the turmeric enhances or negates the anti-inflammatory properties of curcumin in the bladder so please take my recommendation with a grain of salt, or pepper.
T. J. Moynihan, M.D. writes: "Curcumin is thought to have antioxidant properties, which means it may decrease swelling and inflammation. It's being explored as a cancer treatment in part because inflammation appears to play a role in cancer.
Laboratory and animal research suggests that curcumin may prevent cancer, slow the spread of cancer, make chemotherapy more effective and protect healthy cells from damage by radiation therapy. Curcumin is being studied for use in many types of cancer.
Studies of curcumin in people are still in the early stages. Clinical trials are underway to investigate curcumin as a way to prevent cancer in people with precancerous conditions, as a cancer treatment, and as a remedy for signs and symptoms caused by cancer treatments.
Research is ongoing, and there isn't enough evidence to recommend curcumin at this time. As always, talk with your doctor before using any herbal supplement. It's unclear how curcumin may interact with medications."
Knifedealer, thank you for taking the time to reply. Yes, I'm a female, so the all fours position won't work. Thanks for the information on the pepper and turmeric. You have obviously done research on this. The methylprednisolone 4mg prescribed by my doctor seems to be slowly working. Or maybe it's just a matter of time that the cystitis is finally healing on its own. I don't know, but whatever it is, I'll take it. Thanks again for the advice.