This is a tough one. I assume you meant CIS? It IS high grade and, if it came back I would be concerned. I had it, had BCG, and it has not returned. BUT I am constantly turning over in my mind what my choice would be should it come back.
I would think that another opinion would be in order. I am sure the docs at SK are excellent, but I would always wonder how many patients they need to enroll in their trial
You said that cytology indicated that the cancer was back. Have you had another TURB or was this urine cytology? Urine cytology is very useful, but also is subject to a lot of false positives and false negatives, which is why is it used with other diagnostic methods.
CIS is not something to fool around with, so you should collect all the information you can.
Sara Anneg