OK. I doubt your URO has gotten the biopsy back yet showing high grade or low grade and stage? Get a copy of his records (they are the patients property). Often, a second TURB and opinion is done to confirm what is seen and USC will probably do this. Sometimes this can make a big difference on treatment. If this is stage 2, most will tell him to have a cystectomy however, I also read your uncle has some compromised health issues so that might come into play. Directly to your quality of life and expectancy question. There are MANY that have had a cystectomy (some that post here) that are enjoying close to normal lives, and life expectancy. Everyone reacts differently to their situation. Take it one day at a time. That is all you can control.