KathysHeart
The following are points to raise with your husbands urologist and ALL his treating doctors. No recommendation is made here, only issues a that can be raised to obtain a workable treatment plan for your husband. These thoughts are based on my 5 year journey with bladder cancer - you will need the treating doctor's to understand your husbands full situation and determine how to best provide treatment for him.
BCG is not the only option; it is generally accepted as the best initial treatment for non-invasive bladder cancer. When a patient cannot tolerate BCG, or during BCG shortages, other treatments are available. BCG does not work for all patients, and some patients find success with other treatments after BCG failure.
There is a video on this site, an interview with Drs Lamm and O'Donnell, both highly respected. In that interview they back off of some of the "hazards" associated with BCG. It is worth viewing for a further explanation of handling BCG. It is at:
bladdercancersupport.org/bladder-cancer-forum/8-non-invasive-superficial-bladder-cancer-questions-and-comments/34287-bcg-and-septic-systems.html
You may need to involve an oncologist as well as the urologist and your husband's normal care team in finding a workable treatment plan. Make sure that all of the doctors will work together to plan treatment. Make sure that all of the doctors know ALL of the things that need to be considered - the disease, the proposed treatments, the ability of the patient to comply, and urinary habits you have described here. The group of doctors all need to be aware of all the issues.
Mitomycin MIGHT be an option to BCG. It is a chemotherapy drug not a biological, is routinely used for bladder cancers. It can instilled then drained after an hour or so, all at a clinic. It MIGHT avoid the concerning urination issues you describe. Other options exist, depending on the full situation.
Some brief info about Mitomycin is at:
www.cancer.org/cancer/bladder-cancer/treating/intravesical-therapy.html
Hopefully, this will give you a starting point to get a team involved to treat your husband. No recommendation is made her - never accept treatment advice from the internet, but do use what you read as the starting point to discuss options with your doctors.
Only you and the doctors are in a position to decide what is an acceptable treatment plan.
Best,
Jack