Forum

× click the New Topic button to post

Clear Urine Cytology Test

10 years 11 months ago - 10 years 11 months ago #20437 by Rosemary
David,

Which test are you getting, the NMP22 or the Urine Cytology? I've been reading about NMP22, and it seems to me that this is the most ultrasensitive test, AND it can be performed IN HOUSE.

There does seem to be a differential in whether it picks up high or low grade.
And from some of the things that I have read, it sounds like the urine cytology is no better than a cystoscopy alone....

I tell you, I try really hard, but, I do stay confused..
Still, I do feel glad about the results, and as far as trusting my doctor to do the right thing, well, as they say, "No news is good news."

Good to hear from you. Hope you are doing well.

Ro

Rosemary
Age - 55
T1 G3 - Tumor free 2 yrs 3 months
Dx January 2006

Please Log in or Create an account to join the conversation.

10 years 11 months ago #20436 by ddoyle
Rosemary,

Your info on the reliability (or lack thereof) of urine cytology comes as no surprise. Mine have always been negative and invariably the next cysto finds papillary tumors.

Good news about your test, though.

Best wishes,

Your friend,

David

Please Log in or Create an account to join the conversation.

10 years 11 months ago #20426 by maxmag
Hi Rosemary,
Glad to hear things are going well for you.

Regarding this subject,How does the "Urovision" test
fit into all of this?
Stay well,
Max

Max
Age 70
Ta G2
Dx March 2007

Please Log in or Create an account to join the conversation.

10 years 11 months ago #20245 by Rockyiss
Rosemary, Glad your test came out OK ! It is always a good day when the results are neg. Rocky

Please Log in or Create an account to join the conversation.

10 years 11 months ago #20215 by Rosemary
Thanks, Nix.:)

I'm learning more about this disease every day!!

Also, I failed to mention, that combining a urine cytology or NMP22 is more effective at detecting recurrance than a cystoscopy alone.

The primary source for the following information is attributed to the Journal of the American Medical Association and can be found here:

http://www.medpagetoday.com/HematologyOncology/OtherCancers/tb/2506

In a prospective cross-sectional study, the BladderChek test, combined with a cystoscopic examination, detected 99% of all recurrent cancers, according to H. Barton Grossman, M.D., of the M.D. Anderson Cancer Center.


Also, the test alone detected eight of nine cancers that were not found during initial cystoscopy, Dr. Grossman and colleagues reported in the Jan. 18 issue of the Journal of the American Medical Association.


By contrast, the standard urine cytology test, combined with cystoscopy, detected 94.2% of cancers - a rate of detection that was not significantly greater than that of cystoscopy alone, the researchers found.


The BladderChek test, manufactured by Matritech of Newton, Mass., detects elevated amounts of nuclear mitotic apparatus protein, or NMP22, which is released into urine during cell death.


Unlike standard urine cytology, the test for NMP22 does not require whole cancer cells and can be done in a physician's office while the patient waits. It is also cheaper than cytology, the researchers noted.

Rosemary
Age - 55
T1 G3 - Tumor free 2 yrs 3 months
Dx January 2006

Please Log in or Create an account to join the conversation.

10 years 11 months ago #20209 by Nix
thanks for the information, Rosemary. My cytology report has always come back negative, even when CIS was found. I am happy to see there are other tests to check. You always share such helpful information - thanks:)

Nancy S
Ta CIS
dx Ta 11/06
dx Ta CIS 10/07

Please Log in or Create an account to join the conversation.

  • Not Allowed: to create new topic.
  • Not Allowed: to reply.
  • Not Allowed: to add Files.
  • Not Allowed: to edit your message.
Moderators: Cynthiaeddieksara.anne

Users

Total Online: 2 Users and 646 Guests 
Calmdown9's AvatarCalmdown9, tgrocky's Avatartgrocky

Legend: Site Administrator Global Moderator User Banned

Statistics

Today Total Opened: 0 Today Total Answered: 0 Latest User: ninacolada
Yesterday Total Opened: 1 Yesterday Total Answered: 7
Total Posts: 52345 Total Subjects: 6783 Total Users: 8278
Powered by Kunena Forum