Has anyone out there had problems with Mitomycin C? My doc tried BCG last summer with absolutely disastrous results --- bleeding, blisters, almost destroyed the bladder. When things settled down (in the meantime I've had a total of 5 TURBT and a lot more cystos over the past eighteen months) he wanted to try a round of Mitomycin C which he believes is much milder with almost no problems with bad side affects. The first treatment was on Thursday, Sep 11 and the second was yesterday, Sep 19. At first I had no reaction whatsoever, then after about the fourth day some blood -- very minor traces, then some clear matter - maybe tissue or mucous? However, following yesterday's treatment, I've had severe burning, lots of blood, more mucuous blobs and about the worst urgency incontinence I've ever had ( I was completely off all overactive bladder drugs for the past six months!). I have four more MMC treatments scheduled but at this point I'm thinking I should stop at two.
So far there has been no recurrence of the CIS which was removed via TURBT in March of last year but I've had four more TURBT's to remove papillary tumors and to take biopsies of irregular cells which have been dx as dysplasia. I did have a positive FISH test back in Feb of this year but so far no CIS or anything.
Has anyone else out there experienced this type of reaction to Mitomycin C?
David