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whew! finally ! and a question for all

11 years 8 months ago #20915 by michstate89
Rosemary, Thanks for answering the FISH question. I do not get on as often as in the past - new job eats up a lot of time.

David, The FISH test looks for abnormal chromosomal markers from cells in the bladder. FISH can be done on voided samples, but my uro does a bladder wash through the cystoscope. I have had positive results from the bladder and from the ureters, but visual inspection have all been negative. Since then I have seen Dr. Lamm (I live close to Phoenix) and learned that false positives sometimes happen right after BCG, especially after the first 6 weeks of treatment. All of my FISH results since last summer have been negative.

Ross

Ross M
TaG1 March 06
Recurrence Jan 07
BCG Maintenance after 6 week treatment

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11 years 9 months ago #20750 by becky37
THANK YOU EVERYONE i know we are all different and you caqnt predict my outcome just wanted to know it COULD be possible if others went a while between there occurences. and i feel good that i have more info from you all. sorry i am never online thats why it took so long for me to read and reply. thanks again. becky

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11 years 9 months ago #20734 by Rosemary
This definition of "FISH" was found at Web Cafe. I personally have never had the FISH test and don't know why...

FISH - also on WebCafe: an expert P.F. Bassi, MD, reviews FISH

Florescence in situ hybridization (FISH) is an assay which uses a mixture of fluorescent labeled probes to assess urinary cells for chromosomal abnormalities associated with malignancy.

The FISH method detected cancerous cells in the urine of 81 percent of the patients with bladder cancer,” said Kevin Halling, M.D., a Mayo Clinic pathologist and lead researcher on the study. “By comparison, urine cytology detected cancerous cells in only 57 percent of the patients with bladder cancer. “Most importantly, the FISH test picked up more than 95 percent of the high grade cancers, which are the most dangerous and important group of bladder cancers because they have a high probability of progressing to potentially incurable muscle-invasive bladder cancer,” says Dr. Halling. “With only one exception, the only cancers the test missed were low-grade tumors, which are less dangerous and have only a 3 to 5 percent chance of progressing to a higher stage tumor over five years.” The FISH test also detected recurrence of the cancer three to six months earlier than by the cytology, says Dr. Halling. This earlier detection capability should allow treatment to be initiated earlier and possibly give the patient a greater chance for survival, he said


Here is the web link...

http://blcwebcafe.org/content/view/92/102/lang,english/

Rosemary
Age - 55
T1 G3 - Tumor free 2 yrs 3 months
Dx January 2006

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11 years 9 months ago #20731 by DIB
What is "pos FISH"?

Thanks,
David

Male Dx T1G3 5/08 @ Age 59. TURBT 5/08; TURBT+40 mg MMC 6/08; BCG (6) 7/08-8/08; Cysto & TURBT 9/08; BCG Maint(3) 10/08, 3/09; 7/09; 11/09; 5/10; & 1/11. Clean cystos 2/09, 9/09, 3/10, & 10/10.

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11 years 9 months ago #20703 by michstate89
Congratulations on your good news. I have been almost 20 months cancer free. I had 1 tumor removed in March of 2006, then had a clean cysto in June. Thought everything was ok until checkup in September 2006 and had 4 tumors removed. Moved to a different city in October 2006 and first cysto with new doctor revealed 11 tumors - seems I had a little seeding going on. The new doc removed the tumors, instilled mitomycin after Turb and we started BCG maintenance. Have not had any tumors since Jan 07, but have had some biopsies due to pos FISH - which we found out could be caused by the BCG therapy (as per Dr. Lamm). I was never a smoker, but had exposure to aniline in college as a chemistry major - so really have not had much of a lifestyle change except to pay attention to eating more fruits and vegetables and drinking more water.

If someone had told me 10 years ago about all the cystos and catheters I would have said, "not for me!!!" But now I am glad for all the checkups so at least this disease won't sneak up on me.

Ross

Ross M
TaG1 March 06
Recurrence Jan 07
BCG Maintenance after 6 week treatment

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11 years 9 months ago #20679 by Rockyiss
Glad to hear you are clear! For me I went for ten months before it came back. Rocky

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