Any treatment will affect the kidney. My creatine stays between 1.0 and 1.5, when it gets to 1.5 , I get the "drink more water". If the scan is clean, get an PET and MRI to make sure there is no trace. If there is no trace, I would opt out of any chemo. If it is going to come back it will. If you have no trace, immunotherapy could be the treatment of choice after all the trials . However, the tumors have to have PD-1 cells for Nivolumab to maybe work. All treatment has side effects. If you can avoid it, do. I was considered clean after chemo and then diagnosed 3 more times being clean each time afterwards until it matastisized. Please me know if you have any questions.