Dear Anne,
I was recently diagnosed with TCC though I was fighting the Non-Hodgkin's lymphoma for a long time now (since 1992). There are so many new treatments for lymphomas/leukemias now that sometimes it's hard to chose. When I started looking for similar treatments for TCC I was surprised that for the last decade there was almost no progress. But then I found some new research that just started that will drastically change the front line therapies for this cancer, too. What I tell myself is that I need to hang on for 5 more years and then we will have plenty of wonderful choices. The major progress comes from the monoclonal antibodies specific for each cancer and from engineered car t cells. Both are in development now for the bladder cancer. That will be the medicine of the future. The first monoclonal antibody for the PD-L1 receptor got a breakthrough therapy designation for bladder cancer from the FDA. It might be approved very soon or has been approved already. Please, check the articles section where I put some links about some new research that I found. So, keep your spirits up. I understand that some papers are difficult to understand even for me although I am a biochemist. If you google car t cells it gives you some explanation.