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Oncovite

13 years 7 months ago #2711 by Bob_P
Rosemary,
Thanks for the "leg work" and the web site. Very interesting....I take it that your quote is from his web site so I will check that out.  
Maybe a bone scan would be appropriate if one was taking Oncovite for an extended period of time (to check for osteoporosis or osteopenia)?
I've never been a smoker so I wouldn't have to worry about the smoking/beta-carotene problem.
Bob P

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13 years 7 months ago #2708 by Rosemary
I did some leg work for you...

have read from several reputable sources that doses of vitamin-A in excess of 2,500 IUs a day can actually have an oxidizing effect on tissues and result in DNA damage with an increase in lung cancer and antherosclerosis. I am currently talking Oncovite, 2-tablets/2-times/day which give me a daily intake of 36,000 IUs. I assume that this recommendation is based on a benefit vs risk assessment however are there any recommended laboratory tests, blood/urine, etc. that I should be doing on an ongoing basis to monitor any potential risks?

Vitamin C can at times have an oxidizing effect, and it is true that two studies have found that smokers taking very high doses of beta carotene/vitamin A had an increased incidence of lung cancer. Concern has been raised about vitamin E as well. With this background, I think our use of multiple antioxidants is extremely fortuitous. Our 40% reduction in bladder tumor recurrence, with no increase in the incidence of other tumors, is quite remarkable. We believe that a balanced approach is the way to go -- the thought is that one single agent can throw off this balance and even be counterproductive. This speaks also to the importance of fruits and vegetables in the diet--there are a lot of phytochemicals that are beneficial besides the vitamins they provide.

High doses of vitamin A can, rarely in our experience, cause liver function abnormality. The toxicity of A is reduced by vitamin E. Periodic liver function tests, say once a year, are very appropriate.



Rosemary
Age - 55
T1 G3 - Tumor free 2 yrs 3 months
Dx January 2006

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13 years 7 months ago #2706 by Rosemary
http://www.bcgoncology.com/drlamm/askdr20050920.html


:-X





Rosemary
Age - 55
T1 G3 - Tumor free 2 yrs 3 months
Dx January 2006

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13 years 7 months ago #2705 by Rosemary
Bob,

I just got a 2nd reply to a question that I posed to Dr. Lamm at his website.  (See my thread about Dr. Lamm in Superficial Bladder Cancer) He is very kind to take the time to reply to my questions, as he does for many suffering from bladder cancer.

As it was he who developed the Oncovite, I wonder if you have taken a search of FAQ's at his web site ?
I bet this question has been posed to him before.  

If not, you might write to him.

It is incredible to me, that with all his research and work and as busy as he must be, that he takes the personal time to reply to questions.

I'll be back in a minute with that web site.

Rosemary

 

Rosemary
Age - 55
T1 G3 - Tumor free 2 yrs 3 months
Dx January 2006

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13 years 7 months ago #2703 by Bob_P
After reading some good things about Oncovite's possible reduction of tumor recurrence, I bought a couple of bottles on the Internet.  But now that I read the label I'm wondering how safe it is.
I notice that the Vitamin A content is 9,000 units per tablet.  If I take 4 tablets per day, I'm getting a whopping 36,000 units.
According to the U. of California, Berkeley Wellness Letter, anything over 6,000 units per day may cause bone fractures in people over 50:

"Lower levels of vitamin A. The multi should contain no more than 5,000 IU of vitamin A (that’s 100% of the Daily Value), but at least 40% of this should be in the form of beta carotene (the label will say, for instance, “50% as beta carotene” under vitamin A). Getting more than about 6,000 IU of vitamin A itself from food and supplements increases the risk of fractures in people over 50. Beta carotene is safe for your bones, though high doses (more than in a basic multi) may increase the risk of lung cancer in smokers."

Or do the benefits of new tumor reduction outweigh the risk of the possibility of fractures? Any thoughts on this?

Bob P.

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