This is a very interesting discussion. I remember, a couple years ago reading about a certain gene in family members AND if they are also smokers a corralation for bladder cancer has a high possibility of occurring. I have alerted my four younger brothers who are smokers to have their urine tested since their older sister (me)has had superficial papillary bladder cancer. Since Rosemary's posting of the gene and Warren's comments on the subject I did a search on Yahoo and learned that gene can be the cause of all types of diseases. As far as folate is concerned, the current recommendation is for 400 units but my daughter who is a Registered, Licensed Dietician and others in that nutrition category say the intake should be a minimum of 800 daily. Here is the website that shows lots of different diseased attributed to that MTFHR gene.
www.ihop-net.org/UniPub/iHOP/bng/90334.html?list=0 Rosie