Wife DX with T2 Micropapillary Cancer...

1 year 6 months ago #60228 by sara.anne
Replied by sara.anne on topic Wife DX with T2 Micropapillary Cancer...
We will keep our fingers crossed, James. These new immunotherapy drugs can have amazing results.

Sara Anne

Diagnosis 2-08 Small papillary TCC; CIS
BCG; BCG maintenance
Vice-President, American Bladder Cancer Society
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1 year 6 months ago #60227 by JamesF
Replied by JamesF on topic Wife DX with T2 Micropapillary Cancer...
Met with our oncologist today. She is very concerned with how rapid the second bump on the skull has grown. She decided it is best to begin immunotherapy immediately, so my wife received the first treatment of Pembrolizumab this afternoon. The treatment took less than an hour. She will have a treatment every three weeks. The efficacy of the treatments will be analyzed several weeks after her third installment. Chemotherapy was not prescribed because it was ineffective the first go around before RC, as well as the fact that my wife did not tolerate it very well.

She may have additional radiation treatments for the second bump on her skull as well as her ribs as she is experiencing a lot of rib pain at night. The radiation treatment on her spine seems to have reduced the pain at that location somewhat. She is currently taking Tramadol for the pain.

Okay that should be it for the next few weeks. Will update then unless there are other developments.

Thanks,

James

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1 year 7 months ago #60184 by sara.anne
Replied by sara.anne on topic Wife DX with T2 Micropapillary Cancer...
James, thank you for documenting her journey. Hope it may give guidance to others on the same journey.

Hope the news is good when you meet with the oncologist

Sara Anne

Diagnosis 2-08 Small papillary TCC; CIS
BCG; BCG maintenance
Vice-President, American Bladder Cancer Society
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1 year 7 months ago #60182 by JamesF
Replied by JamesF on topic Wife DX with T2 Micropapillary Cancer...
Just want to continue to document the journey.

My wife completed the radiation on her spine and skull. It was 5 days of treatment with the treatment each day lasting approximately 50 minutes. These treatments were to reduce the pain.

Next meeting will be after Thanksgiving with her primary oncologist. Will see what the plan is then.

Thanks

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1 year 7 months ago #60124 by Alan
Replied by Alan on topic Wife DX with T2 Micropapillary Cancer...
James,

I am sorry about the report I have read. The good news is M.D. Anderson is simply one of the best.

DX 5/6/2008 TAG3 papillary tumor .5 CM in size. 2 TURBS followed by 6 instillations of BCG weekly with a second round of 6 after a 6 week wait.

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1 year 7 months ago #60122 by JamesF
Replied by JamesF on topic Wife DX with T2 Micropapillary Cancer...
Hello All,

I want to continue to update this story in hopes it may be useful to others in the future.

As a reminder my wife was diagnosed in August 2019 with MIBC Stage 2 rare plasmacytoid variant bladder cancer. She underwent 4 treatments of chemotherapy that were not effective. She received a radical cystectomy in January 2020 where the pathology stage was upgraded to 3a with no lymph node involvement and clear margins. She has since had clean scans at 3 and 6 months.

It has now been 9 months since her surgery. Recently my wife had a case of bronchitis so we went to the ER. She mentioned to the doctor that she had a bump on her head. They took a CT scan of her head and discovered that there was cancer in her skull. We just completed a biopsy of her skull as well as a total body bone scan and the 9 month CT scan of her neck to her pelvis. The initial pathology of the biopsy from her head indicated that it is most likely the bladder cancer. The bone scan also found spots on her her ribs, her spine and femur. Oddly enough the CT scan discovered no cancer anywhere else. They are comparing the tissue from the cystectomy to the biopsy sample to verify that indeed the bone cancer originated in the bladder cancer.

The oncologist said this will be the first case she has seen that the initial site of bladder cancer metastasis is in the bones. She was very surprised that the CT scan was clean. Things move very fast at MD Anderson. We met with the radiation oncologist today and had the radiation simulation. She will have radiation treatment next week to the skull and the spot on her spine. Will continue with radiation to the other spots after that.

I am sorry that I can not report a more positive outcome at this time. My wife has a good outlook and is ready for the upcoming battle. I will continue to update this thread on regular intervals as we continue this journey.

Thanks to all!

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