-
Why not change the BCG protocol to lower strength?
I posted the following question to ‘Ask Dr. Lamm’:
If there is evidence that a reduced BCG dosage strength may improve efficacy, why isn’t the protocol changed to start with reduced dosage strength. Seems like fewer people would fail BCG treatment (I failed and had a RC upon recurrence of only CIS) if the dose was lower. Maybe a rat study is warranted on the lower dosage strength?
Here is his response:
There is a lot of work that has been done, both in animal models and clinical trials. BCG is now so effective that it takes thousands of patients to demonstrate that something new is superior. Hard to get funding for reduced dose BCG studies. See my work with Reichert regarding dose response in animals. Don Lamm, MD
Age 54
10/31/06 dx CIS (TisG3) non-invasive (at 47)
9/19/08 TURB/TUIP dx Invasive T2G3
10/8/08 RC neobladder(at 49)
2/15/13 T4G3N3M1 distant metastases(at 53)
9/2013 finished chemo -cancer free again
1/2014 ct scan results….distant mets
2/2014 ct result…spread to liver, kidneys, and lymph system
My opinions are my own and do not reflect the opinion of ABLCS or anyone else. I am not a doctor nor do I play one on TV.0 RepliesSorry, there were no replies found.
Sign In to reply.
