• Posted by alisa8527 on September 23, 2009 at 2:08 am

    my husband has been dx with stage IV bladder cancer with distant mets to liver/and soft tissue/he is only 34, we’ve done the standard chemo’s cisto/gemzar, carbo/gemzar, and the new one is Abraxtin/we went to the U of M today and were offered to try this drug with the chemo has anyone heard anything or had any success on this drug for bladder cancer?

    Leigh replied 15 years, 4 months ago 4 Members · 6 Replies
  • 6 Replies
  • leigh's avatar

    leigh

    Member
    September 23, 2009 at 8:55 pm

    Pat,

    This rational therapeutics makes so much sense…I would certainly investigate that option too.


    Leigh, 39
    Dx July 2007
    TURBT July 2007
    RC/Neobladder ,Studer Pouch, September 2007
    Erasmus Centrum Rotterdam
    TNM Classification: pT4 N2 Mo
    4 cycles aduvant chemo Gemzar & Cisplatinum
  • 's avatar

    Guest
    September 23, 2009 at 8:47 pm

    Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells by Stanford …there is a contact for this article also.

    http://www.pnas.org/content/early/2009/08/03/0906549106.abstract
    you can also see the pDF file.
    Also in Medical Review
    http://www.nlm.nih.gov/medlineplus/news/fullstory_87692.html
    Targeting the specific variety of bladder cancer and pinpointing treatment has always made sense to me…i must be alone on this theory. There is also a group out in Long Beach which does just that
    http://www.rationaltherapeutics.com/patients/content2.aspx?rid=8
    Just things to think about.
    Pat

  • leigh's avatar

    leigh

    Member
    September 23, 2009 at 4:04 pm

    Dear Alisa,

    I can only imagine what you are dealing with at the moment and I am so sorry that you and your husband are in this situation.

    My fear of progressing plays heavy on my heart being diagnosed at stage IV and this drew me to
    your post. Thankfully I have no known mets and remain under close observation.

    I wish I could offer you some information that could help your situation. Having to decide what
    is best for your husband with regards to trials must be very heart wrenching.

    Best wishes to your husband with his chemo treatment and I send to you both positive thoughts for
    the future.

    Leigh


    Leigh, 39
    Dx July 2007
    TURBT July 2007
    RC/Neobladder ,Studer Pouch, September 2007
    Erasmus Centrum Rotterdam
    TNM Classification: pT4 N2 Mo
    4 cycles aduvant chemo Gemzar & Cisplatinum
  • cynthia's avatar

    cynthia

    Administrator
    September 23, 2009 at 3:13 pm

    Alisa,

    I am so sorry to hear of your situation. There are trials going on the have the hope of promise but none that are shining star candidates that I know of at this time. The links for searching for clinical trials is at this link. I am sorry that we can’t offer more help but know that we are here to listen and to offer support.

    http://bladdercancersupport.org/index.php?option=com_content&view=article&id=406


    Cynthia Kinsella
    T2 g3 CIS 8/04
    Clinical Trial
    Chemotherapy & Radiation 10/04-12/04
    Chemotherapy 3/05-5/05
    BCG 9/05-1-06
    RC w/umbilical Indiana pouch 5/06
    Left Nephrectomy 1/09
    President American Bladder Cancer Society
  • Alisa8527's avatar

    Alisa8527

    Member
    September 23, 2009 at 2:17 pm

    does anyone know of any clinical trials that have a promising result?

  • 's avatar

    Guest
    September 23, 2009 at 3:38 am

    alisa…Sutent has been used in many trials…breast cancer and colon cancer and those trials have been discontinued. But it seems to be a first line for renal cell metastatic cancer

    http://www.urotoday.com/38/browse_categories/renal_
    cancer/pfizers_sutent_is_recommended_as_firstline_
    treatment_for_kidney_cancer_patients_by_british_health_
    agency.html

    Pat

Sign In to reply.