Home › Forums › All Categories › Non Invasive Bladder Cancer › “Signet Ring Differeniation”

  • Alan

    Member
    December 8, 2020 at 1:07 am

    The type you have is aggressive. I would move forward sooner if possible. Might even be good to get a second opinion for fresh eyes and peace of mind.

    DX 5/6/2008 TAG3 papillary tumor .5 CM in size. 2 TURBS followed by 6 instillations of BCG weekly with a second round of 6 after a 6 week wait.

  • busaman

    Member
    December 8, 2020 at 12:43 am

    My urine lab from 11/27/20 (post turbt/biopsy, 6 bcgs, and cystoscopy after which uro said everything looks good) now shows: Suspicious for high grade urothethlial carcinoma. I do another urine lab before I see my uro for follow-up cystoscopy in January (the “every three month” exam). Any comment?

  • Alan

    Member
    December 1, 2020 at 9:15 pm

    I second Sara Anne’s comments. This is a rare cancer and does need follow up. Glad your follow up was clean!

    DX 5/6/2008 TAG3 papillary tumor .5 CM in size. 2 TURBS followed by 6 instillations of BCG weekly with a second round of 6 after a 6 week wait.

  • busaman

    Member
    December 1, 2020 at 9:00 pm

    ok thnx

  • sara.anne

    Member
    December 1, 2020 at 8:58 pm

    I would ask him about this.

    Sara Anne

    Diagnosis 2-08 Small papillary TCC; CIS
    BCG; BCG maintenance
    Vice-President, American Bladder Cancer Society
    Forum Moderator

  • busaman

    Member
    December 1, 2020 at 8:57 pm

    part of my path report from june 2020 said this Bladder Neck Invasive high grade urothelial carcinomoa with signet ring differentiation.

    I since had my bcg therapy and the follow up scope. the uro said he was very pleased, everything looked clean, and no recurrence of tumors. i am no scheduled for scopes every three months.

    He never said anything to me about “signet ring differentiation.”

  • sara.anne

    Member
    December 1, 2020 at 8:38 pm

    Where did you see this? Was in one of your path reports? If so, your urologist needs to discuss this with you yesterday.

    Signet ring differentiation is a very rare finding in bladder cancer that can occur with either adenocarcinoma of the bladder or with the more common urothelial carcinoma that most of us have. It is not particularly good news and should lead to a referral to a very specialized cancer center.

    Sara Anne

    Diagnosis 2-08 Small papillary TCC; CIS
    BCG; BCG maintenance
    Vice-President, American Bladder Cancer Society
    Forum Moderator

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