Home Forums All Categories Newly Diagnosed, New To The Forum Mike’s crazy theory on BPH and Bladder cancer

  • Mike’s crazy theory on BPH and Bladder cancer

    Posted by mmc on February 18, 2010 at 6:42 pm

    Did you have enlarged prostate issues prior to bladder cancer?

    Actually, calling all guys who have or have had bladder cancer, did you have enlarged prostate prior to getting bladder cancer and did it affect frequency and completeness of voiding?

    ..and calling all women, did you have any urinary retention issues prior to having bladder cancer?

    I sent a note to my surgeon (at a bladder cancer center teaching hospital) about doing a study.

    My theory is that people who have urine retention issues (don’t always void completely) are at higher risk.

    The study I saw on the link of BPH is flawed (IMHO). They indicated that there was a higher incidence of bladder cancer in patients who had a TURP. Kind of like it’s the TURP’s fault. My theory is that the people who get a TURP are the ones who are fed up with the urinary frequency and urgency issues and therefore they have the type of BPH that constricts the urethra.

    Therefore, men with BPH that constricts the urethra should be more vigilant about other symptoms and more closely watched by a urologist OR should be treated for that condition sooner in order to reduce the increased risk of bladder cancer. That could prevent some occurences and cause others to be caught sooner.

    Again, my point is that it is the lack of complete voiding on a regular basis (regardless of the cause but in men the primary cause is BPH) is the true culprit. Lack of complete voiding means that any and all carcinogens, that the body tries to filter out, sit in the bladder exposing its surface to higher concentrations of carcinogens for longer periods of time.

    I know I had about two years of UTIs that were not UTIs prior to finally being diagnosed. Had I been informed by my GP that having the type of BPH I had could increase bladder cancer risk and that if I got unexplained UTIs….

    Do we have any urologists that act advisors to ABLCS? If so, maybe we can give them the same idea for a study. I think this could actually do some good for some people in the future. Of course, I could very well be wrong. Lord knows it has happended before . But, that’s the reason for scientific studies under controlled conditions. To prove this kind of thing to be right or wrong.

    Mike


    Age 54
    10/31/06 dx CIS (TisG3) non-invasive (at 47)
    9/19/08 TURB/TUIP dx Invasive T2G3
    10/8/08 RC neobladder(at 49)
    2/15/13 T4G3N3M1 distant metastases(at 53)
    9/2013 finished chemo -cancer free again
    1/2014 ct scan results….distant mets
    2/2014 ct result…spread to liver, kidneys, and lymph system

    My opinions are my own and do not reflect the opinion of ABLCS or anyone else. I am not a doctor nor do I play one on TV.
    vgau replied 14 years, 4 months ago 10 Members · 31 Replies
  • 31 Replies
  • vgau

    Member
    February 25, 2010 at 8:43 pm

    George,
    Loved your idea and it is great to have someone like you that reminds us to laugh.
    Thanks,
    Vi


    Dx 10/5 Non Invasive Papillary
  • gkline

    Member
    February 25, 2010 at 1:38 pm

    I am SO GLAD that you all went with this hijack. I can certainly see that you all have the same twisted sense of humor that I have. I sometimes think I am the only one “out there”
    Glad to know you are with me

    George


    Light a man a fire and he is warm for an evening.
    Light a man ON fire and he’s warm forever.

    08/08/08…RC neo bladder
    09/09/09…New Hip
    =
    New Man! [/size]

  • webs

    Member
    February 24, 2010 at 5:58 pm

    Is that what that little purple alien was doing? :angry: Will have to drop kick him the next time I see him. :P

    If you can’t laugh you cry, I’d rather laugh at least the laugh lines are pretty. :kiss:

    Webs

  • Guest
    February 24, 2010 at 5:41 pm

    Reminded me of the movie “Passion Fish”….Great movie..probably more of a chick movie but anyway there is one scene where a soap actress gets her big break in a B Alien movie and she has one line….”I didn’t ask for the Anal probe”
    and she proceeds to give a dozen different readings of it..hysterical
    1. i DIDN’t ask for the anal probe?
    2 I didn’t ask for the anal probe!!!!
    3. i didn’t ask for the ANAL probe…
    4. i didn’t ASK for the anal probe??
    and so on…….
    :side:
    pat

  • mmc

    Member
    February 24, 2010 at 3:24 pm

    George,

    Alien probes are already a well known cause of cancer.
    However, less than 1% of aliens do anything with the bladder as they seem to have a particular fondness for anal probes.

    :P

    Mike


    Age 54
    10/31/06 dx CIS (TisG3) non-invasive (at 47)
    9/19/08 TURB/TUIP dx Invasive T2G3
    10/8/08 RC neobladder(at 49)
    2/15/13 T4G3N3M1 distant metastases(at 53)
    9/2013 finished chemo -cancer free again
    1/2014 ct scan results….distant mets
    2/2014 ct result…spread to liver, kidneys, and lymph system

    My opinions are my own and do not reflect the opinion of ABLCS or anyone else. I am not a doctor nor do I play one on TV.
  • gkline

    Member
    February 24, 2010 at 2:28 pm

    I have this crazy theory about bladder cancer.

    I was visited one evening by a silver disc shaped flying machine that made no noise and had flashing lights that paralyzed me into a trancelike state. A tiny purple man came out and zapped me in the bladder area with a tiny ray gun. Two months later…. bladder cancer.

    I have been reluctant to reveal this until now. But I think the people on this site may have had similar experiences.
    :lol: :lol: :lol: :lol: :lol: :lol: :lol: :lol: :lol:

    April 1st will be here soon

    George…. or ….as I am known on ZXenON…. Yusleig


    Light a man a fire and he is warm for an evening.
    Light a man ON fire and he’s warm forever.

    08/08/08…RC neo bladder
    09/09/09…New Hip
    =
    New Man! [/size]

  • wsilberstein

    Member
    February 23, 2010 at 2:14 am

    HPV? If so, another risk factor I never had.


    -Warren
    TaG3 + CIS 12/2000. TURB + Mitomycin C (No BCG)
    Urethral stricture, urethroplasty 10/2009
    CIS 11/2010 treated with BCG. CIS 5/2012 treated with BCG/interferon
    T1G3 1/2013. Radical Cystectomy 3/5/2013, No invasive cancer. CIS in right ureter.
    Incontinent. AUS implant 2/2014. AUS explant 5/2014
    Pediatrician
  • Guest
    February 22, 2010 at 11:18 pm

    Yeah…but it only works on some strains.
    pat

  • mmc

    Member
    February 22, 2010 at 11:15 pm

    Could be. At least they have a vaccine for HPV now.

    Mike


    Age 54
    10/31/06 dx CIS (TisG3) non-invasive (at 47)
    9/19/08 TURB/TUIP dx Invasive T2G3
    10/8/08 RC neobladder(at 49)
    2/15/13 T4G3N3M1 distant metastases(at 53)
    9/2013 finished chemo -cancer free again
    1/2014 ct scan results….distant mets
    2/2014 ct result…spread to liver, kidneys, and lymph system

    My opinions are my own and do not reflect the opinion of ABLCS or anyone else. I am not a doctor nor do I play one on TV.
  • Guest
    February 22, 2010 at 11:03 pm

    OK..my crazy theory is HPV is responsible for bladder cancer(or some of it)…many people carry the HPV and don’t know it.
    http://www.sciencedaily.com/releases/2007/09/070925102651.htm
    and a study in 2007 printed in JAMA
    Data from a national study suggests that about one in four U.S. females between the ages of 14 and 59 years may have the sexually transmitted infection human papillomarivus (HPV), according to a study in the February 28 issue of JAMA.
    But who wants to admit it?? :unsure:
    pat

  • mmc

    Member
    February 21, 2010 at 11:48 pm

    Warren,

    I certainly agree. I do think that it may be just one more risk factor.

    Kind of like everybody who smokes or smoked knows some people that lived to be in their 90’s without ever getting cancer.

    I’m sure millions of people have retention issues but will never get bladder cancer. Similarly, some people with absolutely no known risk factors at all will wind up getting cancers and other diseases.

    Or, lots of people will have atherosclerosis but never have a heart attack or stroke.

    I just think that the more risk factors we can identify, the more we can figure out if we can do something about it or not.

    Thanks!
    Mike


    Age 54
    10/31/06 dx CIS (TisG3) non-invasive (at 47)
    9/19/08 TURB/TUIP dx Invasive T2G3
    10/8/08 RC neobladder(at 49)
    2/15/13 T4G3N3M1 distant metastases(at 53)
    9/2013 finished chemo -cancer free again
    1/2014 ct scan results….distant mets
    2/2014 ct result…spread to liver, kidneys, and lymph system

    My opinions are my own and do not reflect the opinion of ABLCS or anyone else. I am not a doctor nor do I play one on TV.
  • wsilberstein

    Member
    February 21, 2010 at 11:24 pm

    Dear Mike,
    Interesting and plausible theory, but certainly not the answer for all causes either.
    I never had BPH, and even with my urethral stricture problems have always successfully emptied my bladder with each void. I tend to go freqeuntly, so holding it a long time isn’t the issue. I never smoked although my father smoked heavily when I was a child. My father also had a benign bladder polyp, but before we jump on heredity or second hand smoke, my identical twin who grew up in the same smoky house has not had bladder cancer, thank God. I do not work with chemicals. My twin teaches chemistry and did smoke when he was younger.
    As much as we know about disease, as a physician I realize that once we get past what we do know, we still can’t explain the variability of how disease presents and why patient A fares well, patient B does poorly, and patient C doesn’t get what A & B had.


    -Warren
    TaG3 + CIS 12/2000. TURB + Mitomycin C (No BCG)
    Urethral stricture, urethroplasty 10/2009
    CIS 11/2010 treated with BCG. CIS 5/2012 treated with BCG/interferon
    T1G3 1/2013. Radical Cystectomy 3/5/2013, No invasive cancer. CIS in right ureter.
    Incontinent. AUS implant 2/2014. AUS explant 5/2014
    Pediatrician
  • mmc

    Member
    February 19, 2010 at 7:28 pm

    Jim: U crack me up! :D

    KC: Thanks for the info. Score 1 more for the retention issue.

    Webs: Yes, I know about that part but have no idea how to prove that with a study. Maybe that’s why you ladies pee when you laugh hard…holding it too much. :)

    Karen: You’re not late to the party at all. This is just getting started. You are an example of why I included women in my original question. I figure that urethral strictures or just plain constricted urethras would also contribute to the problem. I know my sister and my daughter both needed to have theirs stretched at a young age due to problems. Score another for retention issues.

    Mike


    Age 54
    10/31/06 dx CIS (TisG3) non-invasive (at 47)
    9/19/08 TURB/TUIP dx Invasive T2G3
    10/8/08 RC neobladder(at 49)
    2/15/13 T4G3N3M1 distant metastases(at 53)
    9/2013 finished chemo -cancer free again
    1/2014 ct scan results….distant mets
    2/2014 ct result…spread to liver, kidneys, and lymph system

    My opinions are my own and do not reflect the opinion of ABLCS or anyone else. I am not a doctor nor do I play one on TV.
  • Karenb

    Member
    February 19, 2010 at 7:15 pm

    Know this is a little late in response to your question. I did have post void urine retention and extreme urgency prior to dx of bc. In fact, urol couldn’t do cystoscope in office couldn’t get scope in. Had to be done as outpatient cause urethra needed to be stretched and his operative report with first biopsy stated that there was still a lot of urine in my bladder even thoug I had voided prior to procedure and had not had anything to eat or drink since midnight the night before.
    After talking with him at followup, I realized that is why I had felt the seemingly almost constant full bladder for quite some time, maybe a year. After the procedure, I realized that the amount I had been urinating was hadn’t been the full amount in my bladder for a while.

  • kcnorthstar

    Member
    February 19, 2010 at 6:44 pm

    Mike,

    Interesting topic. I had never been to a urologist until a year before I was diagnosed with BC. I went in because of trouble urinating and was diagnosed with an enlarged prostate. 1 year later I had BC.

    KC


    Age 59
    DX Jan 2006 – T1B G3
    RC – Neobladder June 2006
Page 1 of 3

Log in to reply.