BCG Reaction

Will,

If the reactions are increasing, ask about reducing dose strength.
According to Dr. Lamm, even a 10% solution shows no reduced efficacy.

My reaction was so strong that I was not allowed to continue. Very high fever for days, shakes, etc.

My local uro wouldn't to the reduced dose and I was too naive to argue at that time so they just switched me to mitomycin for a few treatments and then waited for it to come back invasive two years later. If I knew then....

Mike

I've been reading posts for so long you'd think I'd remember these discussions, but I don't. Last time I had BCG a year ago for my first recurrence of CIS I had a reaction to the last treatment. This time I just finished the third BCG/Interferon treatment and I'm having dysuria, frequency, constant burning & pain, and generally feeling crappy as a result. Pyridium, Urelle, ibuprofen, and wine take the edge off. My last treatment was Thursday. It's Monday now and every time I think I'm getting better the symptoms return with a vengeance. Perhaps the fact that I have to catheterize myself Saturday and Monday so that my most recent stricture will stay open for the treatments adds to the irritability. I don't see how I'll be able to hold the treatment in my bladder for 2 hours feeling the way I do, to say nothing of my anxiety about escalation of the reaction. So, has anybody had to delay or interrupt treatment for a reaction? If so, what happens?
- Warren