The BCG worked great for me. Yes there was blood and urgency problems, but all in all I centainly could tolerate it. Then I got Reiders sydrome know as reactive arthritis from my immune system's reaction. What a pain...literally. So for maintenance the doctor decided to switch me to mitomyicin C, which is supposed to have very little reaction. Well I got my first instillation today. I followed the directions by not drinking water for 12 hours and taking a lot of baking soda to raise my urine PH. Now the problem... It really bothers me. My urgency to urinate is double BCG. I already have some blood. My bladder hurts and it never did with BCG. I have read the literature that says that that is pretty common with mitomyicin and should pass when treatment stops, but then I have read that a lot of people never get over the bladder pain and urgency to urinate after Mitomyicin. Its as if the mitomyicin did permanent damage.So... do any of you have experience with mitomyicin? I would prefer the arthritis over what I am going through now. Comments?