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2nd opinion on slides -- still no grade #

8 years 1 month ago #34773 by mmc
Kimberly,

If your BCG is the same day as the concert, you could skip one and make it up later. Sometimes they have to skip it if there is blood in the urine or any other situation going on. If it is a couple of days before the concert, it will likely not be a problem.

Mike

Age 54
10/31/06 dx CIS (TisG3) non-invasive (at 47)
9/19/08 TURB/TUIP dx Invasive T2G3
10/8/08 RC neobladder(at 49)
2/15/13 T4G3N3M1 distant metastases(at 53)
9/2013 finished chemo -cancer free again
1/2014 ct scan results....distant mets
2/2014 ct result...spread to liver, kidneys, and lymph...

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8 years 1 month ago #34684 by Patricia
here's an interesting article on von brunns nests...can be a stumper for some pathologists...read all the way down
http://www.nature.com/modpathol/journal/v22/n2s/full/modpathol2008201a.html

pat

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8 years 1 month ago #34683 by Kimberly
Thanks, jj and Mike. Both pathology reports indicate no muscle invasion, but it was the absence of a number for that grade that had me puzzled. Thanks for explaining the low/high vs. 1-2-3 system.

I had my follow-up today, and we scheduled my 6 BCG treatments starting on 11/17. I'll be done the week of Christmas. Ho! Ho! Ho!

Bad news is that the fourth BCG (Tuesday 12/7) is the same week as my orchestra's Christmas concert. I sure hope I'm able to perform that concert ... joyful music that's not too hard. My heart and soul could really use that.

My uro is following Dr. Lamm's protocol of followup treatments, so he suggested -- assuming that I can tolerate it -- 3-week BCG treatments at the 3-month, 6-month, 9-month and 12-month points. My poor septic tank ...

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8 years 1 month ago #34680 by mmc
JJ is right. I was thinking Stage. Sorry about that.

Age 54
10/31/06 dx CIS (TisG3) non-invasive (at 47)
9/19/08 TURB/TUIP dx Invasive T2G3
10/8/08 RC neobladder(at 49)
2/15/13 T4G3N3M1 distant metastases(at 53)
9/2013 finished chemo -cancer free again
1/2014 ct scan results....distant mets
2/2014 ct result...spread to liver, kidneys, and lymph...

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8 years 1 month ago #34677 by jj803
In bladder pathology there are several different grading systems. I think the one used at JHU is high grade vs low grade so a number is not necessary. This is the most recent WHO recommendation for grading, although many pathologists still use a 3 grade system with 1 = low grade, 3 = high grade, and 2 = intermediate. In the 2 grade system most of what was called 2/3 would become high grade. I think what Mike refers to is stage which is based upon the extent of the tumor: non-invasive, carcinoma in situ, lamina propria only, muscle wall, and beyond muscle wall. Usually, stage is a more important determinant of treatment and prognosis than grade. Best wishes,

jj

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8 years 1 month ago #34667 by mmc
Here is a link to John's Hopkins explaining how to interpret a bladder biopsy pathology report.
http://apps.pathology.jhu.edu/blogs/bladder/?tag=muscularis-propria

Age 54
10/31/06 dx CIS (TisG3) non-invasive (at 47)
9/19/08 TURB/TUIP dx Invasive T2G3
10/8/08 RC neobladder(at 49)
2/15/13 T4G3N3M1 distant metastases(at 53)
9/2013 finished chemo -cancer free again
1/2014 ct scan results....distant mets
2/2014 ct result...spread to liver, kidneys, and lymph...

Please Log in or Create an account to join the conversation.

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