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BCG Plus Interferon

8 years 6 months ago #33402 by Patricia
Hi Brenda...this from Medscape
Combination immunotherapy, specifically the use of BCG plus interferon alfa 2b, is highly effective. About 60% of patients who fail to respond to BCG can be rescued with BCG plus interferon (O'Donnell, Krohn, & DeWolf, 2001). The standard dose is 50 mg to 81 mg of BCG plus 50 million units of interferon alfa 2b. Treatments are given weekly for 6 weeks, with maintenance using up to 3 weekly instillations at 3 or 6 months, and then every 6 to 12 months. The dose of BCG is reduced to 1/3, 1/10, 1/100 as needed to prevent increased side effects. While we try to avoid giving a second 6-week course of BCG to patients who have previously received BCG because they are at risk of immunosuppression, the addition of interferon appears to reduce this risk.
http://www.medscape.com/viewarticle/514530_3
And if that doesn't rescue you ..you know what to do.
Best to you
pat

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8 years 6 months ago #33400 by bmathews9744
I start my second round of BCG next week. The first 6 week course worked for getting rid of the tumor Ta Grade 3 but not the CIS. The second round of BCG will have interferon added.

Does anyone have any experience with this ?

Brenda

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