9 years 7 months ago - 9 years 7 months ago#25448by Patricia
Peg...Surprisingly, low-grade urothelial carcinoma is relatively more responsive to chemotherapy(Mitomycin C) than high-grade carcinoma. In contrast, with BCG immunotherapy, low-grade tumors appear to be relatively less responsive. Therefore, chemotherapy is used initially in low-grade disease, where the risk of progression is very low and the side effects and cost of a single postoperative treatment are also appropriately low. And more doctors are now going with a 6 week regimen of mitomycin C.
So my guess is that O'Donnell did the right thing based on a low grade urothelial carcinoma.......but now that there is progression not necessarily in grade but more tumors....he's going to give the BCG a shot and take a look in there at 6 weeks. I doubt that he would commit to long time treatment at this point as his priority is not letting this demon get out of control.
9 years 7 months ago - 9 years 7 months ago#25444by Peggy R
I'm sorry that I neglected to tell you I had a tumor in the ureter as well as the bladder when they first diagnosed me. My husband reminded me of this after reading a note from Pat last night. Perhaps that was the reason my doc used the Mitomycin in the first place.