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Help? Interpret Path Report

10 years 8 months ago #15456 by sara.anne
Thanks to both of you for the information....for my present purposes, we will assume that I have the mild form, as a result of months of irritation (this is what my uro intimated.) Just can't deal with any more right now!!

Sara Anne

Diagnosis 2-08 Small papillary TCC; CIS
BCG; BCG maintenance
Vice-President, American Bladder Cancer Society
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10 years 8 months ago #15437 by Patricia
sara anne......
Cystitis cystica glandularis is a rare disease, caused by metaplasia of the vesical submucosa, probably related to a chronic irritative factor.[1] Some investigators believe that this condition reflects mobilisation of the humoral immune defence response by various agents.[2] In its minor form, it has the same clinical features as simple cystitis, but its major pseudoneoplastic form may be clinically mistaken for bladder tumour. Cystitis cystica glandularis is considered to be a premalignant disease of the urinary bladder as some reports document its progression to adenocarcinoma. It has also been reported to occur frequently in association with pelvic lipomatosis.[3] Cystoscopic biopsy is mandatory, as the diagnosis is essentially histological. It appears histologically as submucosal nests of columnar epithelial cells surrounding a central liquefied region of columnar degeneration. In the absence of obvious lesion, treatment is usually medical, based on the eradication of the irritative factors. Surgery is required in case of complications of the disease like recurrent haematuria or features associated with bladder outlet obstruction secondary to the pseudoneoplastic growth. The surgical approach includes transurethral resection of the lesion (TUR) or laser ablation.[4],[5] The clinical course is unclear and requires long-term surveillance

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10 years 8 months ago #15433 by ConnieOnAQuest
pathologyoutlines.com gives some information on this

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10 years 8 months ago #15199 by sara.anne
Pat, I understand CIS very well. It is the "cystitis cystica et glandularis" which was the second diagnosis that I wanted to clarify.

Sara Anne

Diagnosis 2-08 Small papillary TCC; CIS
BCG; BCG maintenance
Vice-President, American Bladder Cancer Society
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10 years 8 months ago #15198 by Patricia
sara anne...CIS always high grade...a flat tumor but needs to be treated and watched. Has your doctor recommended BCG? or anything else?
Look under Treatments for Bladder Cancer and you will find info on CIS
Pat

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10 years 8 months ago #15193 by sara.anne
I finally got my copy of the pathology report from my TURB in February which resulted in the diagnosis of CIS. It notes a second finding, "cystitis cystica et glandularis." I have Googled this, and sort of understand that it is a non-malignant irritative thing, but am lost beyond that. Can anyone decipher this for me?
Is it a very common bladder state or is it related to the problems that lead to BC?

Thanks

Sara Anne

Diagnosis 2-08 Small papillary TCC; CIS
BCG; BCG maintenance
Vice-President, American Bladder Cancer Society
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