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Familial Bladder Cancer?

12 years 1 month ago #12705 by timb
For what it's worth, my father died from bladder cancer four years ago during the time that I was being treated. His illness was much more advanced when it presented but, still, I think it had a part to play in my cystectomy decision. My doc said their was no hereditary link known.

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12 years 1 month ago #12700 by driscolls
Gman,
Thanks for the info on bladder cancer and heredity. I certainly plan on doing more research as this is very worrisome to me.

Also, please know I will keep you in my prayers. I hate this dreadful disease, but such much can be done to keep it contained. Follow your gut feelings and stay strong!

Debi

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12 years 1 month ago #12699 by Patricia
Well actually i meant you and your brother as one and Carolyn the nurse who just got her neobladder from Dr. Koch in Indianapolis...she has an identical twin sister.
That is a rather good name for that gene!! Pat

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12 years 1 month ago #12696 by wsilberstein
Dear Rosemary,
Oops! :-[ And I tried to get the link right so it would make things easier :P, but the other article was good too.
Not raining on LI today, but not so nice.
-Warren


Dear Pat,
Another set of twins here? How did I miss that? I always enjoy comparing notes with other twins.
-Warren

P.S.: My niece & my brother had another fun name for the MTHFR gene. Use your imagination because I can't put it on a public forum.
P.P.S.: The MTHFR gene had us worried, but the baby is just fine - 6 months old and adorable.

-Warren
TaG3 + CIS 12/2000. TURB + Mitomycin C (No BCG)
Urethral stricture, urethroplasty 10/2009
CIS 11/2010 treated with BCG. CIS 5/2012 treated with BCG/interferon
T1G3 1/2013. Radical Cystectomy 3/5/2013, No invasive cancer. CIS in right ureter.
Incontinent. AUS implant 2/2014. AUS explant...

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12 years 1 month ago #12688 by Patricia
What i find interesting is that i have now seen two sets of identical twins on this forum..of which..only one of the twins has bladder cancer in each case.....obviously they have the identical genetic make-up but environmental differences....so is anybody studying identical twins? Pat

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12 years 1 month ago #12687 by Rosemary
I just noticed the word "stongly" in the following quote from the referenced link...I wonder why this isn't talked about/researched a little more???

Our results [glow=red,2,300]strongly[/glow] suggest that polymorphisms of the MTHFR and MS genes act together with low folate intake and smoking to increase bladder cancer risk. These results have important implications for cancer prevention in susceptible populations

http://carcin.oxfordjournals.org/cgi/content/full/25/9/1639

Rosemary
Age - 55
T1 G3 - Tumor free 2 yrs 3 months
Dx January 2006

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