Mom was diagnosed w Muscle Invasion Bladder Cancer

12 years 7 months ago #39178 by Cynthia
Leo, what you are describing as the suggested treatment for your mother is probably what is known as a bladder sparing protocol pioneered in the US and still under investigation at Massachusetts General Hospital in Boston for at least 15 or more years. While not the first line of treatment for muscle invasive bladder cancer it is used in very select patients (no P53 over expression, single tumor of expectable location, no CIS) and the elderly. After full removal of the tumor they use radiation and low levels of chemotherapy and a longer systemic chemotherapy regime following full response in the clinical trials. In the elder they often use the low level chemotherapy and radiation after full removal of the tumor. Here is a link to the most current trail.

www.clinicaltrials.gov/ct2/show/NCT00238420?term=NCT00238420&rank=1

There is much written about bladder cancer treatments in the elderly if you Google that term you will find many results such as these. Doctors are many times trying to balance quality of life and the person’s tolerance for standard treatment when dealing with the elderly patient who has bladder cancer.

www.medscape.com/viewarticle/540087

www.asco.org/ascov2/Meetings/Abstracts?&vmview=abst_detail_view&confID=54&abstractID=20545

While taking low level chemotherapy I was told that it might thin, fall our or stay the same and I have talked to people who have experienced any of the above and it also depends on the drugs used so ask. Tell your Mother that I have lost my hair twice to chemotherapy and both times it came back and was nicer than it was before. Unfortunately like baby hair it went back to normal but was nice while it lasted. I also noticed while I was bald that I given the best seats in restaurants and was once upgraded to first class while flying without asking so there are benefits.

If you do not feel at ease with the treatment path that has been suggested you of course should seek a second opinion to see if there are other options.

We are here for you and will try to help if we can please keep us updated.

Cynthia Kinsella
T2 g3 CIS 8/04
Clinical Trial
Chemotherapy & Radiation 10/04-12/04
Chemotherapy 3/05-5/05
BCG 9/05-1-06
RC w/umbilical Indiana pouch 5/06
Left Nephrectomy 1/09
President American Bladder Cancer Society

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12 years 7 months ago #39177 by Gracie
Sorry to hear about your mom. Xeloda is a chemo drug that is taken orally (tablets) that is low dose. Unfortunately the hair does thin while taking it but the other side effects are much less severe then chemo infusions.

Best of luck. Gracie

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12 years 7 months ago #39176 by Joseph
Hello,

You may consider contacting Sylvester Comprehensive Cancer Center.
They are running a trial delivering targeted chemotherapy directly to cancerous cells, sparing the rest of the body the deleterious side effects.

sylvester.org/news-events/press-releases/out-of-options-first-patient-in-bladder-cancer-trial-now-has-hope

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12 years 7 months ago #39169 by leolion811
My Mom was just diagnosed with Muscle Invasion Bladder Cancer this past week. We met with the Radiation Oncogolist on Friday and she is scheduled for 7 weeks, 5 days a week, 20 minutes each day of radiation. Tomorrow we are meeting with the chemo doctor to discuss her treatment plan. They are talking about a low dose chemo treatment plan-what does that mean? Mom just turned 87 years old (some birthday present, right?) and decided not to have her bladder removed-too invasive for her age. Does anyone know what low dose chemo drugs that would be good for her that doesn't have too many side effects? She doesn't want to lose her hair :( I have been researching different info on the chemo treatment but I would like some opinions from you on what to suggest to the doctor tomorrow. This is soooo overwhelming to absorb everything but I am doing the best that I can. And to top it off, we had a earthquake and hurricane this past week. Such a terrible week for all family. Thank you!

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