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Muscle is missing from biopsy

1 week 1 day ago #58472 by Alan
I was looking at the thread and i see you asked about my grade and must have missed the question. I was TAG3 papillary. CT scans are very common to be sure nothing else in the urinary tract has problems. The good news for your father is he is on the way to beating this.

DX 5/6/2008 TAG3 papillary tumor .5 CM in size. 2 TURBS followed by 6 instillations of BCG weekly with a second round of 6 after a 6 week wait.

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1 week 1 day ago #58471 by Reyoflight03
Update: no cancer in the muscle biopsy!
*does a back flip*

He did however have a CT because he wound up in the hospital with severe pain following the biopsy.

The CT showed a 1.7 cm adrenal nodule which they are saying is “unrelated” so he is having an MRI tomorrow to look at it.

Looks like BCG treatments are starting today! (He is high grade)

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3 weeks 5 days ago #58340 by Reyoflight03
Hi Alan, thank you for the input. Everything has me so nervous. He’s going to try to get the biopsy done at Moffit in Tampa but with it being high-grade it seems like everything is time sensitive. If you don’t mind me asking; what was the grade of you diagnosis ?

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4 weeks 11 hours ago #58328 by Alan
Reyoflight 03,

Welcome. I had the same issue with my first TURB. It is a delicate cutting and burn procedure. The first pathology sample didn't not have enough muscle. However, in a diagnosis as yours, a second is usually done regardless and I did have a second which included muscle. So, this is common. Let us know how the second goes.

DX 5/6/2008 TAG3 papillary tumor .5 CM in size. 2 TURBS followed by 6 instillations of BCG weekly with a second round of 6 after a 6 week wait.

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4 weeks 18 hours ago #58327 by Reyoflight03
Hey all! I’m new here.

My 56 y/o father was recently diagnosed with bladder CA; however they cannot determine the stage just yet due to no muscle being present in the biopsy.

It is confirmed that it has invaded the lamina propria and the cells are high grade urothelial papillary carcinoma ; however, the doctor THOUGHT he dug deep enough to have muscle fragments and the pathology showed that there actually were none to test.

Now he needs to go to another biopsy to have the muscle collected for proper staging.

Is this common, has this happened to anyone, or do we have a surgeon that doesn’t know the site of detrusor muscle?

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