Mike\'s crazy theory on BPH and Bladder cancer

14 years 1 month ago #30455 by wsilberstein
Replied by wsilberstein on topic Mike\'s crazy theory on BPH and Bladder cancer
HPV? If so, another risk factor I never had.

-Warren
TaG3 + CIS 12/2000. TURB + Mitomycin C (No BCG)
Urethral stricture, urethroplasty 10/2009
CIS 11/2010 treated with BCG. CIS 5/2012 treated with BCG/interferon
T1G3 1/2013. Radical Cystectomy 3/5/2013, No invasive cancer. CIS in right ureter.
Incontinent. AUS implant 2/2014. AUS explant 5/2014
Pediatrician

Please Log in or Create an account to join the conversation.

14 years 1 month ago #30452 by Patricia
Replied by Patricia on topic Mike\'s crazy theory on BPH and Bladder cancer
Yeah...but it only works on some strains.
pat

Please Log in or Create an account to join the conversation.

14 years 1 month ago #30451 by mmc
Could be. At least they have a vaccine for HPV now.

Mike

Age 54
10/31/06 dx CIS (TisG3) non-invasive (at 47)
9/19/08 TURB/TUIP dx Invasive T2G3
10/8/08 RC neobladder(at 49)
2/15/13 T4G3N3M1 distant metastases(at 53)
9/2013 finished chemo -cancer free again
1/2014 ct scan results....distant mets
2/2014 ct result...spread to liver, kidneys, and lymph...

Please Log in or Create an account to join the conversation.

14 years 1 month ago #30449 by Patricia
Replied by Patricia on topic Mike\'s crazy theory on BPH and Bladder cancer
OK..my crazy theory is HPV is responsible for bladder cancer(or some of it)...many people carry the HPV and don't know it.
www.sciencedaily.com/releases/2007/09/070925102651.htm
and a study in 2007 printed in JAMA
Data from a national study suggests that about one in four U.S. females between the ages of 14 and 59 years may have the sexually transmitted infection human papillomarivus (HPV), according to a study in the February 28 issue of JAMA.
But who wants to admit it?? :unsure:
pat

Please Log in or Create an account to join the conversation.

14 years 1 month ago #30428 by mmc
Warren,

I certainly agree. I do think that it may be just one more risk factor.

Kind of like everybody who smokes or smoked knows some people that lived to be in their 90's without ever getting cancer.

I'm sure millions of people have retention issues but will never get bladder cancer. Similarly, some people with absolutely no known risk factors at all will wind up getting cancers and other diseases.

Or, lots of people will have atherosclerosis but never have a heart attack or stroke.

I just think that the more risk factors we can identify, the more we can figure out if we can do something about it or not.

Thanks!
Mike

Age 54
10/31/06 dx CIS (TisG3) non-invasive (at 47)
9/19/08 TURB/TUIP dx Invasive T2G3
10/8/08 RC neobladder(at 49)
2/15/13 T4G3N3M1 distant metastases(at 53)
9/2013 finished chemo -cancer free again
1/2014 ct scan results....distant mets
2/2014 ct result...spread to liver, kidneys, and lymph...

Please Log in or Create an account to join the conversation.

14 years 1 month ago #30425 by wsilberstein
Replied by wsilberstein on topic Mike\'s crazy theory on BPH and Bladder cancer
Dear Mike,
Interesting and plausible theory, but certainly not the answer for all causes either.
I never had BPH, and even with my urethral stricture problems have always successfully emptied my bladder with each void. I tend to go freqeuntly, so holding it a long time isn't the issue. I never smoked although my father smoked heavily when I was a child. My father also had a benign bladder polyp, but before we jump on heredity or second hand smoke, my identical twin who grew up in the same smoky house has not had bladder cancer, thank God. I do not work with chemicals. My twin teaches chemistry and did smoke when he was younger.
As much as we know about disease, as a physician I realize that once we get past what we do know, we still can't explain the variability of how disease presents and why patient A fares well, patient B does poorly, and patient C doesn't get what A & B had.

-Warren
TaG3 + CIS 12/2000. TURB + Mitomycin C (No BCG)
Urethral stricture, urethroplasty 10/2009
CIS 11/2010 treated with BCG. CIS 5/2012 treated with BCG/interferon
T1G3 1/2013. Radical Cystectomy 3/5/2013, No invasive cancer. CIS in right ureter.
Incontinent. AUS implant 2/2014. AUS explant 5/2014
Pediatrician

Please Log in or Create an account to join the conversation.

Moderators: Cynthiaeddieksara.anne